Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gli3  GLI-Kruppel family member GLI3   (Synonyms: Bph, brachyphalangy)
Results	Reference
1*	J:108509 Blaess S, Corrales JD, Joyner AL, Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809
1	J:121232 Bok J, Dolson DK, Hill P, Ruther U, Epstein DJ, Wu DK, Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear. Development. 2007 May;134(9):1713-22
1	J:87223 Buttitta L, Mo R, Hui CC, Fan CM, Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development. 2003 Dec;130(25):6233-43
1	J:313289 Dias JM, Alekseenko Z, Jeggari A, Boareto M, Vollmer J, Kozhevnikova M, Wang H, Matise MP, Alexeyenko A, Iber D, Ericson J, A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells. Sci Adv. 2020 Sep;6(38)
1*	J:49164 Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC, Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
1	J:228881 Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, Kurtulmus B, Novikov O, Spatz J, Pereira G, Hubner W, Brodski C, Tucker KL, Blaess S, Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Dev Biol. 2016 Jan 1;409(1):55-71
1*	J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13
1	J:315774 Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A, A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Dev Cell. 2014 Nov 24;31(4):448-60
1*	J:41684 Lee J, Platt KA, Censullo P, Ruiz i Altaba A, Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development. 1997 Jul;124(13):2537-52
1	J:293331 Martinez-Chavez E, Scheerer C, Wizenmann A, Blaess S, The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration. Development. 2018 Dec 17;145(24):dev166033
1*	J:170258 Mavromatakis YE, Lin W, Metzakopian E, Ferri AL, Yan CH, Sasaki H, Whisett J, Ang SL, Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
1	J:95326 McDermott A, Gustafsson M, Elsam T, Hui CC, Emerson CP Jr, Borycki AG, Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. Development. 2005 Jan;132(2):345-57
1	J:193395 Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK, The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013 Jan 17;152(1-2):210-23
1*	J:60986 Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL, Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
1	J:316612 Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP, Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev. 2012 Dec 15;26(24):2802-16
1	J:238372 Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM, A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Cell Rep. 2016 Jun 28;16(1):66-78
1*	J:40390 Sasaki H, Hui C, Nakafuku M, Kondoh H, A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development. 1997 Apr;124(7):1313-22
1	J:105832 Svard J, Henricson KH, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway. Dev Cell. 2006 Feb;10(2):187-97
1	J:199133 Tang M, Luo SX, Tang V, Huang EJ, Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development. Neural Dev. 2013;8:8